Maarten L Simoons Selected Research

Platelet Membrane Glycoproteins

4/2007	Effects of platelet glycoprotein IIb/IIIa receptor blockers in non-ST segment elevation acute coronary syndromes: benefit and harm in different age subgroups.
6/2004	Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial.
7/2002	Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
7/2002	Sustained ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation: incidence, predictors, and outcomes.
6/2002	Early angioplasty in acute coronary syndromes without persistent ST-segment elevation improves outcome but increases the need for six-month repeat revascularization: an analysis of the PURSUIT Trial. Platelet glycoprotein IIB/IIIA in Unstable angina: Receptor Suppression Using Integrilin Therapy.
1/2002	Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting: results from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
1/2002	Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials.
1/2002	Characteristics, treatment and outcome of patients with non-ST-elevation acute coronary syndromes and multivessel coronary artery disease: observations from PURSUIT (platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrelin therapy).
7/2001	Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study.
7/2001	Systematic adjudication of myocardial infarction end-points in an international clinical trial.

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Maarten L Simoons Research Topics

Disease

41	Myocardial Infarction 12/2015 - 07/2001
40	Acute Coronary Syndrome 01/2019 - 07/2001
31	Coronary Artery Disease (Coronary Atherosclerosis) 03/2016 - 01/2002
21	Cardiovascular Diseases (Cardiovascular Disease) 12/2015 - 07/2003
18	Heart Failure 12/2015 - 06/2002
11	Unstable Angina 08/2009 - 07/2001
9	Ischemia 12/2015 - 02/2003
9	Coronary Disease (Coronary Heart Disease) 03/2015 - 01/2005
9	Stroke (Strokes) 09/2013 - 02/2004
8	Inflammation (Inflammations) 12/2016 - 01/2004
7	Heart Arrest (Cardiac Arrest) 12/2015 - 04/2007
6	Hemorrhage 09/2013 - 01/2002
5	Cardiogenic Shock 01/2014 - 08/2009
5	Infarction (Infarctions) 12/2012 - 06/2002
5	Necrosis 05/2010 - 04/2003
5	Chest Pain (Chest Pains) 02/2007 - 03/2003
4	Diabetes Mellitus 07/2013 - 06/2002
4	Hypertension (High Blood Pressure) 08/2012 - 06/2002
3	Left Ventricular Dysfunction 08/2011 - 01/2006
3	Vascular Diseases (Vascular Disease) 03/2011 - 04/2009
3	Myocardial Ischemia (Ischemic Heart Diseases) 12/2009 - 02/2003
3	Death (Near-Death Experience) 12/2009 - 09/2005
2	Cardiomyopathies (Cardiomyopathy) 08/2011 - 11/2007
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 03/2011 - 08/2010
2	Thrombosis (Thrombus) 05/2009 - 04/2004
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 11/2007 - 01/2005
2	Reperfusion Injury 02/2007 - 03/2004
2	Thrombocytopenia (Thrombopenia) 12/2004 - 05/2003
1	Drug-Related Side Effects and Adverse Reactions 12/2015
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 03/2015
1	Atrial Fibrillation 09/2013
1	Ventricular Fibrillation 08/2011
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 08/2011
1	Ventricular Tachycardia 08/2011
1	Non-ST Elevated Myocardial Infarction 01/2011
1	ST Elevation Myocardial Infarction 01/2011
1	Hyperglycemia 09/2010
1	Coronary Stenosis (Coronary Artery Stenosis) 03/2010

Drug/Important Bio-Agent (IBA)

21	Perindopril FDA LinkGeneric 03/2016 - 07/2005
15	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 03/2016 - 07/2005
11	Biomarkers (Surrogate Marker)IBA 01/2019 - 07/2003
10	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 03/2016 - 11/2007
10	Platelet Membrane GlycoproteinsIBA 04/2007 - 07/2001
9	C-Reactive ProteinIBA 01/2019 - 03/2003
9	Eptifibatide (Integrilin)FDA Link 06/2004 - 07/2001
8	Dobutamine FDA LinkGeneric 01/2014 - 10/2004
8	Troponin T (Troponin T1)IBA 02/2007 - 06/2002
6	Abciximab (ReoPro)FDA Link 01/2006 - 02/2003
6	Glycoproteins (Glycoprotein)IBA 05/2004 - 01/2002
5	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2010 - 07/2003
4	Pharmaceutical PreparationsIBA 01/2012 - 01/2002
4	CD40 Ligand (CD40L)IBA 01/2006 - 03/2003
4	Trinitrotoluene (TNT)IBA 01/2006 - 03/2003
3	pro-brain natriuretic peptide (1-76)IBA 01/2019 - 07/2003
3	TroponinIBA 01/2019 - 03/2003
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2015 - 08/2006
3	CholesterolIBA 07/2013 - 06/2002
3	CytokinesIBA 05/2009 - 04/2003
3	MB Form Creatine KinaseIBA 08/2007 - 01/2006
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2006 - 02/2003
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2005 - 02/2003
3	Heparin (Liquaemin)FDA LinkGeneric 12/2004 - 05/2003
3	Streptokinase FDA Link 02/2004 - 07/2002
2	BradykininIBA 03/2014 - 03/2011
2	Antihypertensive Agents (Antihypertensives)IBA 03/2011 - 04/2009
2	Glucose (Dextrose)FDA LinkGeneric 09/2010 - 12/2006
2	Nitroglycerin (Dynamite)FDA LinkGeneric 11/2009 - 04/2009
2	CreatinineIBA 02/2007 - 06/2002
2	Creatine Kinase (Creatine Phosphokinase)IBA 02/2007 - 01/2006
2	AntibodiesIBA 12/2004 - 05/2003
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 02/2004 - 01/2004
2	Dalteparin (Dalteparin Sodium)FDA Link 02/2004 - 08/2003
1	LDL Receptors (LDL Receptor)IBA 03/2015
1	Vasodilator Agents (Vasodilators)IBA 03/2014
1	Bradykinin B1 ReceptorIBA 03/2014
1	Bradykinin Receptors (Bradykinin Receptor)IBA 03/2014
1	des-Arg(9)- bradykininIBA 03/2014
1	EnoximoneIBA 01/2014
1	LDL CholesterolIBA 01/2014
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2014
1	PTX3 proteinIBA 11/2013
1	AntithrombinsIBA 09/2013
1	Warfarin (Coumadin)FDA LinkGeneric 09/2013
1	Dabigatran FDA Link 09/2013
1	caplacizumabIBA 07/2011
1	AngiotensinogenIBA 03/2011
1	Kallikreins (Kallikrein)IBA 03/2011
1	Prorenin ReceptorIBA 03/2011
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 05/2010
1	Coenzyme A (CoA)IBA 01/2010
1	candesartanIBA 01/2010

Therapy/Procedure

32	Therapeutics 03/2016 - 07/2001
10	Percutaneous Coronary Intervention 07/2013 - 06/2002
8	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 07/2013 - 01/2002
8	Secondary Prevention 08/2011 - 07/2006
3	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 08/2011 - 01/2005
3	Thrombolytic Therapy 03/2004 - 01/2003
2	Resuscitation 01/2014 - 09/2007
2	Drug Therapy (Chemotherapy) 08/2012 - 07/2008
1	Blood Transfusion (Blood Transfusions) 07/2013